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Abstract

QUALITATIVE ANALYSIS AND Α-AMYLASE INHIBITION ASSAY OF AQUEOUS FOLIAR EXTRACT OF LANTANA CAMARA (LINN)

Debapriyo Bhowmick, Dr. Garima Bartariya and Abhishek Kumar*

ABSTRACT

Lantana camara (Linn) is native to the American tropics. It belongs to
verbena family. It also displays antimicrobial, fungicidal, insecticidal
properties. It has also been used in traditional herbal medicines for
treating a variety of ailments, including cancer, skin itches, leprosy,
rabies, chicken pox, measles, asthma and ulcers. The present study was
carried out on foliar extract of Lantana camara (Linn) to find their
significance in diabetic therapeutic studies. The conducted work was
based on phytochemical analysis and in-vitro α-amylase activity. High
concentration of glucose in the blood causes a metabolic disorder
which is known as diabetes. High concentration of glucose in blood
may damage many of the body’s systems that is why diabetes is a chronic disease. Result of
qualitative analysis exhibited that this plant contains flavonoids and phenol in leaves but
amino acid, alkaloids, and saponins were absent. The phytochemicals present in plants are
responsible for preventing disease and promoting health have been studied extensively to
establish their efficacy to understand the underlying mechanism of their action. Result of this
study revealed that leaves extract showed α-amylase inhibition in a dose dependent manner.
The extracts showed maximum inhibition at a concentration of 5 mg/ml and which is
decreased with decreasing concentrations i.e. 2.5 and 1 mg/ml. In conclusion, more research
is required for developing a potential and valuable antidiabetic therapy by using α- amylase
inhibition.

Keywords: Lantana camara, Flavonoids, Alkaloids, ?-amylase, Phytochemical.


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