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            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

DIABETES: QUANTUM ANALYSIS OF THE INTERACTIONS OF CARNOSINE AND OTHER DIPEPTIDES VS. GLUCOSE

Dr. Manuel Gonzalez-Perez*

ABSTRACT

The treatments with carnosine and other peptides have revolutionized
science in recent years. Researchers show that treatment with carnosine
improves glucose (GLU) metabolism, albuminuria, and pathology. The
objective of this research was to analyze the chemical-quantum
interactions of GLU with pure amino acids (AAs) and dipeptides. The
hyperchem simulator was used to perform quantum calculations. These
calculations are based on the Electron Transfer Coefficient (ETC). The
following discoveries were made: the GLU is very aggressive and can
attack any AA in its pure state. GLU also attacks dipeptides,
polypeptides, and biological tissue. Carnosine has an ETC = 33.824,
and there are other dipeptides with lower ETC. All dipeptides of
Histidine (His) keep their ETC value = 33.824 constant, which is the
ETC value of carnosine. It concluded that all dipeptides of His must
have similar behavior to carnosine. Laboratory studies of these His
dipeptides are suggested in order to control blood GLU and nephropathies for diabetic
patients.

Keywords: Diabetes, Quantum chemistry, Carnosine, Dipeptides, Glucose.


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