WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

IMPROVEMENT BY THE AQUEOUS EXTRACT OF THE LEAVES OF DESMODIUM VELUTINUM WILL DC (FABACEAE) OF BIOLOGICAL PARAMETERS ALTERED BY ETHANOL 30 % IN RATS

Etou Ossibi A. W.*, Elion Itou R. D. G., Epa C., Mbougou Bouesse B., Gouollaly Tsiba, Okemy Andissa N. and Abena A. A.

ABSTRACT

Most epidemiological data show that regular alcohol consumption is
related to an increase the occurrence of cardiovascular diseases,
dysfunction of noble organs and changes in biochemical and
hematological parameters. The objective of this work is to evaluate the
effects of the aqueous extract of the leaves of D. velutinum on the
consequences of the subchronic excessive consumption of ethanol 30
% in the wistar rat. Alterations in biological parameters (rat weight,
noble organ masses, ALT, ASAT, white blood cells, red blood cells,
hemoglobin and platelets) were induced by ethanol overload 30 %
daily for eight (8) weeks. The detection of flavonoïds in this extract
was made by Thin Layer Chromatography (TLC). At the doses of 250
and 500 mg/kg the aqueous extract improves the biological parameters.
This extract contains flavonoïds. Other activities to deepen the effects of the aqueous extract
of the leaves of D. velutinum on the alterations of the biological parameters induced by the
ethanol 30% deserve to be realized.

Keywords: Ethanol 30%, Desmodium velutinum, toxicity, biological parameters, flavonoïds.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More