WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

PREVALENCE OF IRON DEFICIENCY IN CHILDREAN WITH FEBRILE SEIZURE

Nobo Krishna Ghosh*, Farhana Tanjin, Forhad Monzur, Farhana Rizwan, Morsheda Khanam, Azmeri Sultana, Bijoy Chakraborty and Kazi Touhidul Alam

ABSTRACT

Objective: Febrile seizures are one of the most common neurologic problems during infancy and childhood periods, occurring in 3-4% of the children with a recurrence rate of 30 to 40%. They occur rarely before 6 months and after 5 years of age, with a peak incidence between 14-18 months of age which overlaps with that of iron deficiency anemia which is from 6 to 24 months. General objective of this study is to determine prevalence of iron deficiency in children with febrile seizure. Methods: The study was conducted in the Department of Pediatric Medicine, Institute of child health & Shishu Sasthya Foundation, Mirpur, Dhaka over a period of 6 months from August 2016 to January 2017. A structured data collection form was developed containing all the variables of interest which was finalized following pretesting. Data were collected by interview, observation, clinical and laboratory testing. Results: In the study it has been found that over half (51.3%) of the simple febrile patients had a history of iron deficiency compared to 45% of the complex febrile seizure patients. The comparison was not statistically significant between groups with respect to iron deficiency (p = 0.648). Over 28% of simple febrile seizure patients had a history of recurrence of febrile seizures compared to 20% of complex febrile seizures. The comparison did not turn to significant with respect to recurrence of febrile seizure as evident by p = 0.493. Laboratory investigations shows that mean hemoglobin, PCV, mean corpuscular volume, mean corpuscular hemoglobin, serum iron concentration, serum ferritin level and total iron binding capacity were 9.7 ± 1.4 gm/dl (range:6.8 – 14.2), 30.7 ± 4.6% (range:22 – 44), 67.9 ± 7.1 fl (range:53 – 88), 24.7 ± 4.7 pg (range:15.5 – 33.0), 22.1 ± 0.9 μg/dl (range:14.3 – 38.0), 5.6 ± 1.3 μg/L (range:2.3 – 32.4) and 566 ± 25 μg/dl (range:290 – 963) respectively. Thirty nine percent of patients had hemoglobin level less than 9 gm/dl, 35.6% mean corpuscular volume less than 65 femtoliter, 64.4% mean corpuscular hemoglobin less than 28 picograms per cell and 49.2% serum ferritin level less than 12 μg/L. Conclusion: The prevalence of iron deficiency in febrile seizures among hospitalized children is high compared to that in developed countries and is mainly attributed to low and middle socioeconomic status. The simple febrile seizure is the most frequent type of febrile seizure and patients with iron deficiency and risk of recurrence of febrile seizures are higher in simple febrile seizure than complex febrile seizure.

Keywords: Febrile Seizure, Iron Deficiency in Children.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More