WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DIAZOTISED SULPHANILIC ACID REAGENT FOR THE DETERMINATION OF THIAMINE IN AQUEOUS SOLUTION – APPLICATION TO PHARMACEUTICAL PREPARATIONS

Dawood H. Mohammed* and Hadeel Mustafa

ABSTRACT

A simple, precise, accurate, high reproducible and economical visible spectrophotometric method of analysis for the determination of thiamine was developed and validated. The proposed method involves diazotization of sulphanilic acid under acidic conditions in presence of sodium nitrite, followed by its coupling with thamine in alkaline medium. The absorption spectra of the yellow colored formed between thiamine and positive diazonium ion has absorption maximum at 405 nm. The linear regression analysis data for the calibration plot showed good linear relationship (r = 0.9969) with in the concentration range of (2 –26)μg mL-1. With molar absorption1.0253×104 L.mol-1.cm-1. The method was successfully applied in the evaluation of thymine in pharmaceutical preparation.

Keywords: .


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More