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Abstract

EVALUATION THE ACTIVITY OF GLUCO HERB DM2 AS NATURAL DRUG AGAINST DIABETES MELLITUS (TYPE 2) AS COMPARISON STUDY WITH METFORMIN DRUG

Firas T. Abd, Ali K. Abbood, *Ibrahim S. Abbas, Ali H. Salih, Ghadah J. J. Alsallami and Ikbal H Alnagar

ABSTRACT

Over the last century, food habits and human life style have drastically changed which lead to various chronic disease. Diabetes mellitus is one such disease which is causing serious problems to human heath. Hence focus has been turned to words the traditional system of medicine. Medicinal plants play an important role in the management of diabetes mellitus. The aim of this study was evalution of gluco herb DM2 as natural agent which approval from herbal medicine central of Iraqi ministry of health giants Diabetes mellitus this natural drug included three medicinal plant were Artemisia vulgar, Trigonella foenum-gracun and Coriadrum sativum this study included 320 patients newly diagnosed type2 diabetes mellitus and 60 health subjected as control. Patients were randomized into two group, first group included 160 treated with metformin 850mg three times daily, befor meal, group 2 also included 160 patients were treated with gluco herb DM2 500mg (2capsul size 250mg) three times meal, before male. Blood samples were used for determination lipid profile, fasting blood glucose, alanine aminotransferase and serum creatinine. The results of this study were showed the significant effect of gluco herb MD2 on fasting and after 2hr Pstprandial blood glucose levels. The significant reduction in fasting and postprandial blood glucose levels were observed in treated patients after 4 and 8 weeks treatment when compared with 1=0 zero level values (before treatment). Also the gluco herb DM2 was gave significant decreasing of LDL and significant increasing of HDL-C with decreasing of TG after 4 weeks of treatment when compared to zero level values. Metformin 850mg was gave significant effete in all parameters. With the results of gluco herb DM2 is a consider best than metformin. and recommendation, this natural drug may be better and more safety than synthetic oral hypoglycemic agent can produce serious side effects.

Keywords: Diabetes Type 2, Metformin, gluco herb DM2.


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