WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

IN SILICO STUDIES ON DENGUE AND MARBURG VIRAL PROTEINS WITH SELECTED MURRAYA KOENIGII LEAVES CONSTITUENTS

Rameen Taj S., Sheetal V. Rao, Tulasi D. P., Nisha R., Pavithra K. and *Balasubramanian Sathyamurthy

ABSTRACT

Dengue and Marburg virus contains seven and six proteins respectively, which are considered to be the most effective for drug designing. Recent studies have shown that these proteins can effectively cause the inactivation of dengue and Marburg disease in humans. Phytochemicals present in Murraya koenigii can be used to prevent premature graying of hair and kidney pain. It has got antibacterial activity, anti fungal activity, anti protozoal activity. In this particular study, the binding efficiency of 5 compounds present in the Murraya koenigii with all the thirteen viral proteins was performed through in silico methods. By our molecular docking result, we found that the 2-Phenyl-4 Quinolinecarboxamide have highest binding affinity with the proteins and we also predicted the binding site amino acid residues and the type of hydrogen bonding.

Keywords: Murraya koenigii, molecular docking, binding affinities, 2-Phenyl-4 Quinolinecarboxamide.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More