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Abstract

A REVIEW ON ESTIMATION OF LORCASERIN HYDROCHLORIDE IN BULK AND TABLET DOSAGE FORM

Chetan Kedari*, Hemlata Bhavar and Sagar Magar

ABSTRACT

Obesity is a metabolic dysfunction associated with a wide range of chronic illnesses that cause significant increases in comorbidity and premature mortality, impaired quality of life and large healthcare costs. According to the World Health Organization, Obesity is a leading preventable cause of death worldwide, with increasing rates in adults and children. In 2015, 600 million adults (12%) and 100 million children were obese in 195 countries. Obesity is more common in women than men. These numbers are likely to increase exponentially in the future. Due to this scenario, it is important to highlight the available treatments for obesity and to assess their effectiveness. Although obesity is an ancient disease, studies are constantly being conducted to improve treatment effectiveness, reduce side effects of any current medications, and identify new therapeutics targets. Because the treatment of obesity is constantly evolving, treatment can be quite a challenge. Lorcaserin hydrochloride is use as antiobesity drug. Lorcaserin hydrochloride is available in tablet dosage form it is important to estimation this drug from dosage form. This review is focus on estimation of Lorcaserin hydrochloride in bulk and tablet dosage form by using RP-HPLC and UV Spectrophotometric method.

Keywords: Lorcaserin Hydrochloride, RP-HPLC, UV-Spectroscopy.


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