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Abstract

STANDARDIZATION OF THE DRUG CHUKKU NEI – A SIDDHA POLYHERBAL FORMULATION

Dr. M. Lavanya*, K. Suresh, M. Meenakshi Sundaram and V. Banumathi

ABSTRACT

The Aim of this study was to standardize the Siddha formulation- Chukku nei by following modern scientific quality control procedures both for the raw material and the finished product. Chukku nei was subjected to macro-microscopic, Physicochemical, preliminary phytochemical, TLC and HPTLC analysis was carried out as per the WHO guidelines to fix the quality standards of this drug. This study results a set of diagnostic characters essential for its standardization. The iodine value is 172.08mgI2/g indicates it is not too much hard in texture. The saponification value is 262.43 mh KOH/g to neutralize the fatty acids resulting from the complete hydrolysis of 1gm of sample. The pH is found to be 4 that is weakly acidic. The acid value was found to be 3.104 mg KOH/g, the peroxide value is 2.325meq/kg comparatively very low and has long shelf life. The drug was free of from specific pathogen, microbial contamination, heavy metals, aflotoxin and pesticide were below the deductible limit. The values obtained after physicochemical parameters study showed that these values should be helpful to develop new pharmacopoeial standards. The physicochemical and phytochemical constituents found to be present in raw material is used for the preparation of Chukku nei possibly facilitate the desirable therapeutic efficacy of the medicinal formulation.

Keywords: Chukku nei, Physicochemical analysis, Standardization, Siddha medicine.


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