WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SURFACTANTS - THE ASTOUNDING NANOMATERIALS IN THE DRUG DELIVERY SYSTEM

Purushottam Ghosh*

ABSTRACT

Nanotechnology can be defined as the technology which has allowed for the control, manipulation, and manufacture of materials in very small size range. Surfactants take on novel properties in micellization of biologically active substances that have low toxicity and high solubilization power towards poorly soluble pharmaceuticals to aid in large number of therapeutic protocols such as gene therapy, drug delivery, drug targeting. However, surfactants are used to reduce toxicity and side effects of drugs but this carrier systems impose various limitations like lack of target specificity, altered effects and diminished potency due to drug metabolism in the body, cytotoxicity of certain anti-carcinogenic pharmacological agents. Biocompatible surfactants with optimized physical, chemical and biological properties can serve to overcome the limitations faced in drug delivery systems by understanding the interactions of this nanomaterials with the biological environment, cell-surface receptors, drug releasing process and stability of the therapeutic agents. These newer generations of drug delivery systems have significant advantages over the other drug delivery systems. This article discusses the need for nanotechnology-based drug delivery systems, their advantages, applications, classification and limitations of such drug delivery.

Keywords: Surfactant, nanomaterial, nanotechnology, nanoparticle, micellization, cytotoxicity.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More