WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS OF SOME NOVEL 2- SUBSTITUTED BENZIMIDAZOLE DERIVATIVES & THEIR ASSESSMENT FOR ANTIMICROBIAL & ANTHELMINTIC ACTIVITY

Ashish Senapati, Rosan Patel, Lohit Kanta, Sanat Kumar Sahu and *Chaitanya Prasad Meher

ABSTRACT

Heterocyclic compounds are the greatest invention by the scientists in the present scenario. Now-a days they are the ultimate goal for solving several health complexities. Presence of hetero atoms in a molecule as pharmacophore is responsible for wide variety of therapeutical activity. Objective of this work is to improvement of humble and relaxed method for generation of 2-substituted benzimidazole derivatives. It involves insertion of aromatic aldehyde into the 2nd position of benzimidazole nucleus. Which results a number of derivatives. Each derivatives were interpreted through IR spectroscopy & evaluated for antimicrobial & anthelmintic activity. Antimicrobial activity was confirmed by disc diffusion methods. Minimum zone of inhibition (7 mm) was found in case of compound, 2C (E.coli) & Maximum zone of inhibition (14 mm) was found in case of compound 2D (S.aureus) followed by 12 mm in case of 2B (E.coli). All derivatives also found to possess anthelmintic activity when we compare with the a standard drug albendazole.

Keywords: Derivatives, Synthetic, Disc diffusion, anthelmintic.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More