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Abstract

COMPARISON OF THE EFFICACY AND POTENCY OF ORAL CLONIDINE AND TRAMADOL IN PERI-OPERATIVE SHIVERING IN GERIATRIC PATIENTS UNDERGOING TRANS-URETHRAL RESECTION OF PROSTATE UNDER SPINAL ANAESTHESIA

Dr. Umar Jan, Dr. Tahira Akhter*, Prof. Syed Quazi, Dr. Shabir Ahmad Mir, and Dr. Sabina Nisar

ABSTRACT

Background: shivering after subarachnoid block has various deleterious effects. Can be prevented and treated by various non pharmacological and pharmacological methods. Both of these act as synergistic to each other. Objective: To compare the efficacy, potency, hemodynamic effects and side effects of oral clonidine and tramadol in geriatric patients under spinal anaesthesia. Methods: A total of 150 patients undergoing TURP under spinal anaesthesia were randomly divided into GC(50) received oral clonidine 150microgram, GT(50) recieved oral tramadol 50mg, GP(50) recieved placebo preoperatively. In the intraoperative and postoperative period. Grades and incidence of shivering were noted in all three groups and treated if required. Results: Severity grades and incidence were low in group C and group T than group P however goup T had higher incidence and grades than group C. Both decreases incidence and grades of shivering and need of rescue doses. However clonidine is better than tramadol but causes sedation. Conclusion: prophylactic oral clonidine and tramadol are effective in preventing shivering without side effects, with oral clonidine better than tramadol.

Keywords: Shivering, Tramadol, Clonidine, TURP, Subarachnoid Block.


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