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Dr. Sanjivani Wanjari*, Dr. Anil Wanjari, Dr. Priyanka Kumari and Dr. Smriti Baghel


Systemic lupus erythematosus (SLE) is a chronic inflammatory connective tissue disease commonly found in the child bearing age group. More commonly it is diagnosed in young women between the age of 20 and 30 years. It is more common in women than men in the ratio of 9:1. The manifestations of SLE are notoriously variable in its presentation, course, and outcome and there are intermittent periods of exacerbation and remission.[1] (Rahman and Isenberg, 2008). The diagnosis of Lupus is made according to the 1997 revised criteria of the American Rheumatism Association[2] for diagnosis of systemic lupus erythematosus. If any four or more of these 11 criteria are present, serially or simultaneously then the diagnosis can be made. Maternal and foetal mortality and morbidity are considerably increased, compared with the general population.[3] Women with SLE are at higher risk for spontaneous abortions, preeclampsia, preterm delivery and intrauterine growth retardation and neonatal lupus.[4] Multisystem involvement because of the disease process and the treatment itself like steroids, immune-suppressants and anti-coagulants can pose a risk to both the mother and baby.[5]

Keywords: Systemic lupus erythematosus, pregnancy complications, Prednisolone, hypothyroidism, seizures.

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