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Abstract

DESIGN, SYNTHESIS, CHARACTERIZATION & IN-SILICO PREDICTION OF SUBSTITUTED 2-AMINOTHIOPHENE, 1,3,4- THIADIAZOLE AND THIENO[2,3- d] PYRIMIDINE DERIVATIVES

P. L. N. Ranganath*, N. D. Nizamuddin, S. K. Rubina and A. Hemanth

ABSTRACT

Thiophene has a promising role in the chemical pool heterocyclic compounds fused with an other heteroaromatic systems have numerous pharmacological activities like antimicrobial, antiviral, anti-inflammatory, antidiabetic, antioxidant, anticancer, antidepressant, antiplatelet, antituberculosis, anticonvulsants, anti hypertensive, antioxidant and antifungal properties. Keeping this in view, the present work deals the retrosynthesis of some novel Substituted 2- Amino thiophene, 1,3,4-Thiadiazole And Thieno[2,3-d]Pyrimidine derivatives.

Keywords: 2- Amino thiophene derivatives, 1,3,4-Thiadiazole derivatives, Thieno[2,3-d]pyrimidine derivatives.


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