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Abstract

MICROWAVE ASSISTED SYNTHESIS A GREEN APPROACH FOR SYNTHESIS OF BENZOFUSED NITROGEN CONTAINING HETEROCYCLIC DERIVATIVES

A. N. Waghmare* and Amol S. Jagdale

ABSTRACT

This paper aims to review on the detail information about most routinely used greener approach such as microwave assisted synthesis including their mechanism and it is also highlights significant examples where microwave heating provided key advantages over a conventional thermal method. Various advantages of microwave assisted synthesis includes, Rapid reactions, High purity of products, Less side-products, Improved yields, Simplified and improved synthetic procedure, Wider usable range of temperature, Higher energy efficiency, Sophisticated measurement and safety technology, Modular systems enable changing from mg to kg scale. Disadvantages of microwave assisted synthesis includes Heat force control is difficult, Water evaporation, Closed container is dangerous because it could be burst. Various examples are of microwave assisted synthesis as greener approach for synthesis of nitrogen containing benzofused heterocyclic derivatives are given.

Keywords: Microwave assisted synthesis, heterocyclic, quinazoline.


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