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Asl? Mete*, Habip Atalay, Simay Serin, Hülya Sungurtekin and Onur K?l?ç


Intoxication has been an important problem concerned social groups closely since old ages. According to Ministry of Health, in 2001, it was figured out that 11 672 people consulted in health institutes because of the intoxication. Nowadays, most of these cases occur by reason of medical drugs, recreational drug, industrial and agricultural toxics. In this retrospective study, between 2007-2011, we followed up individual properties, etiological factors, the period of admission to the hospital after intoxication, the period in intensive care unit, patients clinical situiation during intensive care, type of toxicity, seasonal distribution of the acute poisoning cases addmitted to the intensive care unit and these factors were evaluated if they were related to mortality or not. Last 5 years, the number patients admitted intensive care unit with the reason of intoxication was 114. Female male ratio was 45,6 /54,4%. Single married ratio was 35/65%. Their average age was 36,1. Cause of the toxication was mostly medicines 52,6%. Herbicide was the second reason (32,5%). The main reason of toxication was suicide (77%). The most common way of poisoning was oral ingestion (90,4%) and 75,2% of patients used actived carbon in initial treatment. Only 15,3% of patients needed mechanic ventilator treatment and average day was 4 days. Glaskow Come Scale 13,13 on admission APACHE II score was 6,6. Mortality rate was 9,6%. There was no seasonal variation. Mortality rate was higher in the groups which, the admission time was more than 12 hours, in cases poisoned by methyl alcohol, needed mechanic ventilator, low GKS was and high APACHE II on admission. As a result, this retrospective study shows paralel results poisoned patient profile in Turkey. The most common cause of poisoning is medical drugs. As a predictor of mortality; patients GKS and APACHE scores on addmition, type of toxicity, by which way it is taken and the time of the admission to the hospital may lead the way.

Keywords: Medical Drugs, Toxicology, ?nstensive Care, Poison.

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