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Abstract

PERINATAL OUTCOME IN PREGNANCIES COMPLICATED WITH THROMBOCYTOPENIA

Dr. Sanjivani Wanjari*, Dr Priyanka Kumari and Dr. Ayesha Master

ABSTRACT

Thrombocytopenia, defined as a platelet count of <1.50 Lacs/cumm, is a common hematologic abnormality during pregnancy, with an incidence of 6.6%.[1] It occurs four times more frequently in pregnancy than in the non-pregnant women population. A low platelet count is often an incidental finding, however it may indicate a coexisting systemic or gestational disorder. Intervention may become necessary in a few cases due to reduce risk to the mother and foetus. The causes of thrombocytopenia in pregnancy are diverse, and the clinical features vary widely. Timely analysis of the cause and appropriate therapy should effectively improve the prognosis of pregnancies. Thrombocytopenia in pregnancy can be classified as mild with a platelets count of 1- 1.5 lacs/cumm, moderate at 50,000 to 1 lacs/cumm and severe at less than 50,000/cumm. Signs of thrombocytopenia usually occurs when platelet counts are less than 50,000/cumm, like petechiae, nose bleeds, haematuria, GI bleeding. Gestational thrombocytopenia is defined as a mild thrombocytopenia, occurring during the third trimester of pregnancy with spontaneous resolution postpartum and no neonatal thrombocytopenia. This is the most common cause of thrombocytopenia during pregnancy but a low platelet can also be associated with several diseases, either pregnancy specific or not, such as preeclampsia, HELLP syndrome, or idiopathic thrombocytopenic purpura (ITP).

Keywords: Thrombocytopenia, pregnancy, low platelets, perinatal outcome, gestational thrombocytopenia.


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