WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE ESTIMATION OF ESCITALOPRAM OXALATE AND TOLTERODINE TARTRATE IN ORAL DOSAGE FORMS

M. Meera Devi*, K. Kalyani, M. Sukanya and H. Padmalatha

ABSTRACT

A new, precise, rapid, accurate HPLC method was developed for the estimation of Escitalopram oxalate and Tolterodine tartrate in oral dosage forms. HPLC method for estimation of drug escitalopram in tablets of Cita S-10 (Cresent) was developed by using Kromosil C18 (250 mm x 4.6 mm) 5 μm column with mobile phase composition of acetonitrile : methanol : ammonium acetate buffer pH 3.0 in the ratio 30:20:50 by isocratic elution technique, the flow rate was 1.0 mL /min and UV detection at 238 nm. The developed HPLC technique is a simple and accurate method for the estimation of API Escitalopram in tablet dosage forms. HPLC method for estimation of drug tolterodine in solid dosage form capsules of Roliten OD (Ranbaxy) was developed by using Kromosil C18 (250 mm x 4.6 mm) 5 μm column with mobile phase composition of acetonitrile: methanol: ammonium acetate buffer pH 3.0 in the ratio 30:30:40 by isocratic elution technique, the flow rate was 1.0 mL / min and UV detection at 281 nm. The correlation coefficient R2 value was found to be 0.9997 for Escitalopram oxalate. HPLC method for estimation of drug tolterodine in solid dosage form capsules of Roliten OD (Ranbaxy) was developed by using Kromosil C18 (250 mm x 4.6 mm) 5 μm column with mobile phase composition of acetonitrile: methanol: ammonium acetate buffer pH 3.0 in the ratio 30:30:40 by isocratic elution technique, the flow rate was 1.0 mL/min and UV detection at 281 nm. The correlation coefficient R2 value was found to be 0.9991 for Tolterodine tartrate.

Keywords: .


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More