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Abstract

A COMPARATIVE CLINICO-PATHOLOGICAL STUDY OF VISHAMA JWARA (MALARIA FEVER) WITH HERBAL FORMULATIONS DRONAPUSPI GHANA VATI„A‟ (LEUCAS ASPERA) & „B‟ (LEUCAS CEPHALOTES)

Dr. Kerketta Anima*, Prof. Dr. Panda Pradip Kumar and Dr. Nayak Utkalini

ABSTRACT

Introduction-In Ayurveda, jwara is defined as the state where the body, mind as well as sense organs suffer due to the high temperature. Vishama jwara is one type of jwara, is an intermittent and complicated type of fever whose signs and symptoms are similar to malaria fever. Material and methods-A single blinded clinical study on 14 patients; Group A- 6 patients and Group B- 8 patients were registered from OPD and IPD of Govt. Ayurvedic College & Hospital, Balangir. They were presented with headache, malaise, intermittent high grade fever since more than one year. Blood sample showed plasmodium vivax and were diagnosed as case of Vishama jwara (malaria fever). They were treated with Ayurvedic formulations of Dronapuspi Ghana vati„A‟ Leucas aspera in Group-A and Dronapushpi Ghana vati „B‟Leucas cephalotes in Group-B, 600mg each thrice a day for a period of 10 days respectively. The subjective and objective parameters were assessed 3 days interval in order to find out the efficacy of formulations by adopting statistical evaluation. Observation and results-It has been observed that in Group-B, 89.35% patients were improved in clinical features (P <0.001) and PV was negative in 62% thick-thin and QBC blood test within 10 days therapy. In Group-A, 84.59% patients were developed clinically (P<0.01) and blood samples showed negative in 50% PV in blood test. Conclusion-The study revealed that the trial drugs (L. cephalotes), Group-B is more effective as compare to Group-A (L .aspera). Maricha, which helps as antipyretic by its deepana, pachana, ushana veerya and jwarahara properties. No adverse effect was seen.

Keywords: Jwara, Vishama jwara, Malaria, Intermittent fever.


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