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Abstract

INVITRO ANTI-ARTHRITIC ACTIVITY OF CROSSANDRA INFUNDIBULIFOMIS LEAF EXTRACT

Sanakattula Sreevani*, P. Pavani Reddy, C. Rajitha Reddy, A. Sowjanya and G. Vinod Kumar

ABSTRACT

The present study have been designed to evaluate the In-vitro Anti- Arthritic activity of herbal plant Crossandra infundibuliformis belonging to the family Acantheacea. The leaves were collected, dried and extracted by soxhlet with solvents like Methanol, Petroleum Ether. The inhibition of protein denaturation by Egg-Albumin method was taken as a measure of the in-vitro anti-arthritic activity. The percentage inhibition of protein denaturation is obtained as 89.4%, 91.2% and 94.3% for petroleum ether extract and 81.8%, 84.3%, 88.5% for methanol extract respectively at a dose of 100, 250, 500 μg/ml. The percentage inhibition of standard diclofenac sodium was found out to be 91.2%, 94.5% and 96.4% respectively at a dose of 100, 250, 500 μg/ml. Pet.ether extract was found to be more effective than Methanolic extract.

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