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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
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Abstract

MEDICATION ADHERENCE TO ANTI TUBERCULOSIS TREATMENT AMONG TUBERCULOSIS PATIENTS IN AN URBAN PRIVATE TERTIARY REFERRAL HOSPITAL: A PROSPECTIVE CROSS SECTIONAL STUDY

Jaisy Jose*, Deepika G., Jisha Helen George, R. Vignesh, Dr. Samhitha Chetty and Dr. R. Ganesan

ABSTRACT

Aim and Objectives: The aim and objective of our study was to investigate the anti- TB treatment adherence rate and to identify factors related to eventual Non Adherence among TB patients during Intensive Phase in an Urban Private Tertiary Referral Hospital using Knowledge Assessment and Medication Adherence Questionnaire. Materials and Methods: A prospective cross-sectional study was conducted in a tertiary care hospital for a period of 6 months. Both outpatients and inpatients having Intensive Phase of Tuberculosis were included. Statistical significance was analysed using chi- square χ2 test with minimum significant level of p< 0.05. Results and Discussion: Our study comprises of 110 patients out of which most patients were in the age group of 56-70 (23.64%). In our study, 90.9% were adhered to the TB treatment regimen after 1st follow up and after counselling and education adherent rate was increased on 2nd follow up (94.5%). The reasons for non-adherence was found to be cost of treatment and transport, side effects of TB drugs, irregular visit, irregular intake of drugs. Most common side effects were itching, rashes, increased Liver Function Test. The level of adherence was measured based on modified Morisky scale through which 67.27% were found to be high adherent, 23.8% were found to be medium adherent, 9% were found to be low adherent. Conclusion: Our study suggests that poor background may influence the patient’s adherence level. The pharmacist provided patient’s education found to have small but significant influence on patient’s adherence and health care outcome.

Keywords: Tuberculosis, Adherence, Resistance.


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