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Abstract

ROLE OF HOMOEOPATHY IN THE MANAGEMENT OF BRONCHIAL ASTHMA: AN OPEN-LABEL INTERVENTIONAL UNCONTROLLED STUDY BASED ON SPIROMETRY EVIDENCE

Sharma Vanija*, Master Farokh J., Jain Tarkeshwar and Jaiswal Prastuti

ABSTRACT

Asthma is a common, chronic respiratory disease affecting 1-18% of the population in different countries, defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness and cough that vary over time and in intensity, together with variable expiratory airflow limitation. This was an open-label experimental uncontrolled evidence based study conducted over 45 patients for period of one and half year at outpatient department of Homoeopathy University, Jaipur. Change in Spirometry values (FEV1) was used as the major evidence for assessing the effect of Homoeopathic remedies. Observing the no. of patients shifting from off- target cases to on- target cases through analyzing the ACT score was another measure to assess the effectiveness of treatment used. After statistical analysis of data it was found that p = 0.000 and Effect size “r” (Cliff‟s delta) = 0.617 for the average changes in the Asthma Control Test after individualized homoeopathic treatment where 100% were off-target before treatment and only 40% after treatment, consequently 0% on-target before treatment and 60% after treatment. Statistically significant difference in FEV1 on an average is 20.11 ± 11.53 with a change in SD from 8.34 before treatment to 15.77 after treatment. One Way ANOVA shows p value 2.77E-11. Cohen’s ƒ2 value is 0.459 reflects large and consistent effect on improvement of FEV1 clinically as well. The value of Spearman’s Rho Coefficient (r) which is 0.83 representing the positive correlation between FEV1 and Asthma Control Test Score. Out of 45 patients, 27 observed marked improvement in Spirometry readings and ACT score. Life functioning and quality was much better after treatment. Study reveals positive role of Constitutional medicines and intercurrent remedies in the difficult cases of asthma and also the constraints of the study e.g. being a short duration trial in the OPD of rural area it lacks the information regarding socio-economic status associated with asthma, more important remedies with their specific potencies in asthma treatment, remedies for managing acute exacerbations, etc.

Keywords: Bronchial asthma, Homoeopathy, Spirometry, Asthma Control Test, FEV1.


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