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Abstract

PHYTOCHEMICAL SCREENING AND ANTIFUNGAL ACTIVITIES OF COMBRETUM RACEMOSUM (P. BEAUV.) (COMBRETACEAE) EXTRACTS AGAINST FIVE CLINICALS FUNGALS STRAINS.

Kamou Kamou Richard, Ouattara Karamoko, Bagré Issa*, Gnahoué Gouéh Ouattara Abou and Coulibaly Adama

ABSTRACT

In an effort to help people get real benefit of the effectiveness of medicinal plants which are less expensive and affordable, aqueous and ethanolic extract of Combretum racemosum has been tested on the in vitro growth of. Aspergillus fumigatus, Aspergillus flavus, Trichophyton rubrum, Trichophyton mentagrophytes and Cryptococcus neoformans The antifungal tests were performed on Sabouraud medium in which the plant extract were incorporated according to the method of inclined tube double dilution. Concentrations were ranging from 200 to 0.78 mg /mL. The results showed that all the extracts tested have led to a significant inhibition of in vitro growth of all the strains. Ethanolic extract showed best antifungal actividy.

Keywords: Combretum racemosum, extraction, antifungal, phytochemical screening.


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