WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

EVALUATION OF ANTIEPILEPTIC ACTIVITY OF METHANOLIC EXTRACT OF OPUNTIA FICUS INDICA FLOWER IN MICE

Kalbant Kumar* and N.C. Nagalakshmi

ABSTRACT

Opuntia ficus indica flowers (L) commonly known as cactus pear Flower, Indian fig Flower, belongs to the Cactaceae family. In the present study, Methanolic extract of Opuntia ficus indica flowers (MEOF) was tested for anticonvulsant activity in albino mice, using different convulsive models. The Methanolic extract of Opuntia ficus indica flowers produced significant anticonvulsant activity in all models studied. The present study also revealed that MEOF increase the concentration of nor-adrenaline and dopamine in brain of mice which attributed to the significant protection against MES induced seizures. Significant results were observed in the estimated parameters thereby justifying the use of this medicinal plant in the treatment of epilepsy.

Keywords: Epilepsy, Opuntia ficus indica, maximal electroshock, pentylenetetrazole, strychnine, seizures, Nor-adrenaline, Dopamine.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More