WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF OFLOXACIN AND ORNIDAZOLE IN COMBINED DOSAGE FORM USING SIMULTANEOUS EQUATION METHOD

Farrel Lisa Gauncar* and Sachi S. Kudchadkar

ABSTRACT

A simple, precise UV spectrophotometric method has been developed for determination of ofloxacin and ornidazole in its tablet dosage form by using distilled water as a solvent. The absorption maximum (λ max) was observed at 287 nm and 318 nm respectively. The method obeys beer lamberts linearity in the range of 2-12 ug/ml for ofloxacin and 5- 30 ug/ml for ornidazole with a value of correlation coefficient (R2) 0.999 for both the drugs at their respective wavelength. Assay was performed on two different brands of marketed formulation. Precision studies were carried out as per ICH guidelines Q2 R1and were found to be within the limits NMT 2 % concluding that the method is precise. The proposed method can be used for routine purity testing in bulk and combined dosage form.

Keywords: Ofloxacin, Ornidazole, OFX, ORN, simultaneous equation method, UV spectrophotometry.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More