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Abstract

3-(BENZO[D][1,3]DIOXOL-5-YL)-3-MORPHOLIN-4-YL-1- PHENYLPROPAN-1-ONE AND ITS METAL COMPLEXES: SYNTHESIS AND EXPLORATION OF THEIR BIOACTIVITY

S. Kannan* and M. Syed Ali Padusha

ABSTRACT

In the current scenario of research bio active metal complexes are gaining huge attention in medicinal organic chemistry. This research article is focused on the flourishing findings of bio activity of metal complexes with newly synthesized ligand. The synthesis, characterization and in vitro evaluation are studied for the metal complexes of 3-(Benzo[d][1,3]dioxol-5-yl)-3-morpholin-4-yl-1- phenylpropan-1-one. The ligand was synthesized by reacting piperonal, morpholine and acetophenone. Various analytical (Chemical assays, TLC and Cyclic voltammetry) and spectral studies (FT-IR, UV-Visible, 1H NMR, and 13C NMR) were employed for the characterization of the ligand and its metal complexes.

Keywords: Mannich Base, Morpholine Derivative, Piperonal, Bioactive Complexes, in Vitro Studies.


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