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Abstract

ANALYSIS OF THE EFFECT OF STEVIOL VS. NITROGEN BASES OF RNA AND DNA USING QUANTUM METHODS

Erick Pedraza-Gress, Karina García-Aguilar, Iliana Herrera-Cantú, Emmanuel Vázquez - López, Juan Jesús García-Mar, Lillhian Arely Flores-González, Manuel Aparicio -Razo, Oscar Sánchez-Parada and Manuel González-Pérez

ABSTRACT

The main component of the Stevia (STV) is steviol [(5β,8α,9β,10α,13α)-13-Hydroxykaur-16-en-18-oic acid]. In recent years Stevia (STV) has aroused the interest of researchers due to high human consumption as an artificial sweetener. In this work, the general objective was to analyze the chemo-quantum interactions of Steviol and nitrogenous bases. As a result of the lowest interaction of Steviol:U2 is ETC =28,872 because of the high probability that Steviol causes a mutation in RNA. This alteration is similar to that caused by nicotine to RNA as well. Another important observation is that Steviol acts as a reducing agent (antioxidant) in all nitrogenous bases; but, it is not reliable; for its low cross-band ETC with U2. In this way, it can be said that not always that a substance is antioxidant, it is good for health.

Keywords: Stevia, Steviol, DNA, RNA, SE-PME, Quantum Chemistry.


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