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Abstract

PURIFICATION AND STRUCTURAL CHARACTERIZATION OF A BIOACTIVE MOLECULE, 13DOCOSENAMIDE,(Z) FROM THE LEAVES OF ERYTHRINA INDICA

R. Priya, P. Mani and S. Maneemegalai*

ABSTRACT

The aim of the study was to isolate a promising anticancer molecule from the leaves of Erythrina indica. The dried leave of this herb was ethanol extracted and fraction separated using HPLC. The fractions were studied for anticancer activity against Adenocarcinomic human alveolar basal epithelial cells (A549). The fraction showed bioactivity was extensively studied for its structural characterization which was identified as 13Docosenamide,(Z) based on the results of FT-IR, NMR, GC and MS/MS studies. Based on the above observation, 13Docosenamide,(Z) is an ideal product for the anticancer therapy which can be easily procured using the lab conditions explored in this investigation.

Keywords: Erythrina indica; 13Docosenamide, (Z); Bioactive; Purification; Structure.


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