WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

PHYTOCHEMICAL AND ANTIMICROBIAL INVESTIGATIONS OF METHANOLIC SEED EXTRACT OF BLACK RICE (ORYZA SATIVA L.) MENTIONED IN AN ANCIENT PALM LEAF MANUSCRIPT (TALAPATRA)

B. Chandramouli, M. Madhavi Latha, K. Narendra and K. Mallikarjuna

ABSTRACT

Plants are being used as an alternative source for the development of safe, effective and inexpensive new drugs to treat and prevent bacterial infections. Recent studies have shown that black rice (Oryza sativa L.) is an important source of nutrients, consumed by most of the world’s population, can suppress some bacterial infections. The use of black rice powder in various ayurvedic preparations was noticed in our ancient palm leaf manuscript. Our current study stems from this observation that black rice seed powder might be having lot of medicinal value. Keeping this in mind, preliminary phytochemical screening of methanolic seed extracts of black rice, Oryza sativa L. was carried out with an intention of finding the type and diversity of phytochemicals present in it. The phyto constituents in the plant were extracted using methanol as solvent. The extracts showed positive results for biologically active compounds like alkaloids, flavonoids, phenols and tannin compounds. The methanolic seed extract of black rice (Oryza sativa L.) was used to evaluate the antimicrobial activities. Antimicrobial activity of methanolic black rice seed extract was evaluated by determining the minimum inhibitory concentration and zone of inhibition. Different pathogenic organisms including 3 gram positive bacteria (B. subtilis, S. aureus and P. pyogenes), 4 gram negative bacteria (P. aeruginosa, K. pneumoniae, Salmonella species and E.coli) and two fungal species (A.niger and C. albicans) were evaluated for antimicrobial activity. The methanolic extract of black rice seed showed high inhibition activity on all 3 gram positive bacteria and greater inhibition activity on Salmonella species among 4 gram negative bacteria. There was no antifungal activity by methanolic seed extract of black rice. This study indicates that the black rice seed contains a variety of chemical compounds that might be contributing to antimicrobial activity, which could be used for food additives and the development of useful natural antimicrobial compounds. As mentioned in our ancient talapatra, this study affirms that black rice grain powder can be used in the preparation of various antimicrobial agents.

Keywords: Black rice, Methanolic extract, Phytochemicals, Flavonoids, Anti microbial activity.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More