INVITRO SCREENING OF ANTI-DIABETIC POTENTIAL OF MIRABILIS JALAPA FLOWERS AND ABELMOSCHUS ESCULENTUS LEAVES
Sunmathy Kanakamani, Saraswathi Uthamaramasamy* and Malathi Mangalanathan
ABSTRACT
Phytochemical analysis of Mirabilis jalapa revealed the presence of
alkaloids, flavonoids, phenols, tannins, saponins and lignins. It is used
in the treatment of skin disease, as an anti-pyretic and anti-parasitic.
Abelmoschus esculentus is the only vegetable crop in Malvaceae
family. It possess diuretic and demulcent property. The present study
was done with an objective to explore the anti-diabetic property of
Mirabilis jalapa (Flowers) and Abelmoschus esculentus (Leaves).The
in vitro Anti-diabetic activity was done by inhibiting alpha-amylase,
glucose diffusion and non-enzymatic glycosylation. The results of the
study revealed that Mirabilis jalapa flower extract exhibited increased
anti-diabetic activity at a concentration of 1000 g/ml than the leaves of
Abelmoschus esculentus. From the observed results, it is concluded
that Mirabils jalapa flowers are good source of phytochemicals which is responsible for its
anti-diabetic activity.
Keywords: Abelmoschus esculentus, Anti-diabetic, Alpha-amylase inhibition, Glucose diffusion assay, Mirabilis jalapa.
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