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Pradyumna Kumar Behera*, Priyambada Rout and Debasish Pradhan


Cirrhosis is chronic injury to the liver from a variety of different sources can result in irreversible scarring of the liver. In developed countries, it is an increasing cause of morbidity and mortality & globally 14th most common cause of death. Among the major cause of chronic liver disease, chronic hepatitis C virus infection is foremost which leads to necroinflammation and fibrosis. Methods like predicting prognosis in patients with Liver Cirrhosis[1] have been developed for assessing liver fibrosis and have been used which are noninvasive. Liver Cirrhosis often have Protein Energy Malnutrition (PEM) and poor physical activity resulting in sarcopenia, which is the loss of skeletal muscle volume and increased muscle weakness. From this review the current understanding of cirrhosis as a dynamic process and outline current therapeutic option for prevention and treatment of cirrhosis complication. By conducting rigourous clinical studies there is need for prevention of liver transplantation in more patients with cirrhosis in future.

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