STUDY OF ANTIOBESITY ACTIVITY OF WITHANIA SOMNIFERA ROOT AND TERMINALIA ARJUNA BARK IN MSG-HFD INDUCED MICE
Kumari Sangita*, Pattnaik Ashok, Chopra M P, Mohanty Satyajit,
Chakraborti Sanchari and K. B. Sulgana
ABSTRACT
Obesity is a major health problem. It is known for the risk factor for
the development of many vital disorder. In this study, the methanolic
extract of Terminalia arjuna and Ethyl acetate extract of Withania
somnifera have been tested for their anti-obesity property. Animals
treated with both plants have reduced the increase in body weight,
periepididymal, fat weight etc. Antiobesity activity produced by plants
are may be also because of inhibition of amylase enzyme, antioxidant
activity, presence of tannins and flavonoid content. Before carrying out
pharmacological activity preliminary phytochemical analysis was
carried out. The plants have shown presence of some common
constituents like saponins, flavonoids steroids tri-terpinoids glycosides
and anthocyanins In this study, both plants are found be beneficial for
the suppression of obesity and associated complications.
Keywords: Obesity, Withania somnifera, Terminalia arjuna, monosodium glutamate.
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