DETECTION OF ANTI-UROLITHIASIS ACTIVITY IN MALLIKAI CHOORNAM USING STRUVITE CRYSTAL GROWTH INHIBITION ASSAY
G. Rathiga*, T. Lakshmi kantham, K. Manikavasakam, V. Banumathi
ABSTRACT
Urolithiasis is one among the three prevalent disorders in the urinary
system. 10 -15% of urinary calculi are formed due to the presence of
urease producing bacteria more prevalent in women. The present study
was aimed to grow struvite crystals in vitro using single diffusion gel
growth technique and to understand the effect of Mallikai Choornam
on its growth. Test drug was prepared at two different concentrations
of 0.5 and 1% dispersed in 1.0M magnesium acetate solution were
gently poured on the set gel in the test tubes to enumerate the growth
inhibition of struvite crystals. In the result of the study, it was
concluded that the test drug Mallikai Choornam has shown inhibitory
activity on struvite crystal growth.
Keywords: Urolithiasis, struvite, crystal growth, Mallikai choornam.
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