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Abstract

ASSESSMENT OF QUALITY OF LIFE AND EFFECTIVENESS OF DIFFERENT THERAPIES IN THE MANAGEMENT OF PSORIASIS AT TERTIARY CARE HOSPITAL IN HYDERABAD

Chavva Bala Sneha*, Banoth Govind, Chapala Mounika, Jowndla Srinivas Reddy, Kameswari Garnepudi and Dr. L. Venkata Narsimha Reddy

ABSTRACT

Aim & Objectives: To assess Quality of life and effectiveness of different therapies in the management of psoriasis with patient counselling. Methodology: This is a prospective interventional study conducted in the Department of Dermatology with a sample size of 94 patients and were divided into two groups based on the intensity of disease i.e., Mild- Moderate and Severe Psoriasis. Based on therapies received mild- moderate psoriatic patients were subdivided into 2, one group received topical therapy, the other group received omega-3 fatty acids along with topical therapy and severe group received Methotrexate, Phototherapy and the combination of Methotrexate + Phototherapy as 3 different groups. SF-36 questionnaire and ZUNG scale were used to assess the quality of life and the presence of depression respectively. SF- 36 questionnaire, ZUNG scale and PASI score calculation was done initially and after 45 days. Improvement in the quality of life was assessed through patient counselling. Results: Data of 94 patients was collected for both zero degree and first degree follow up. The patients demonstrated good compliance with the different combination of therapies. A significant increase after patient counselling in overall quality of life scoring (p=0.0028) was observed. Conclusion: The study showed that use of omega -3-fatty acids along with topical agents in moderate patients has decreased the disease severity by decreasing the comorbid conditions and use of methotrexate along with phototherapy in severe psoriatic patients has decreased the PASI score significantly. This study also showed that providing patient counselling also improved patient’s quality of life irrespective of disease severity.

Keywords: Psoriasis, Patient Counselling, Quality of Life, Omega-3-Fatty Acids, Phototherapy + Methotrexate, Comorbid Conditions.


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