PLATELET INDICES AMONG PATIENTS WITH DIABETIC MELLITUS TYPE 1 AND HYPERTENSION IN KHARTOUM STATE
Hussam MA Ibrahim*, Mohanad Altayeb, Ammar B. Omer, Hind Omar, Shima Abu Obaida, Rowaida El-Zubair, Du’aa Abdul Rahman and Umar Babangida
ABSTRACT
Diabetes and hypertension remains as the most imminent disease contributing
to the cardiovascular disease burden due to ongoing low
grade inflammation. This study was aimed to determine platelet count
and platelet indices in diabetic type 1 patient, diabetic type 1 with hypertension
and hypertensive patient compared with normal individual
to see if there are differences in platelet count and platelet indices
among them. In this study venous blood samples were collected from
healthy control adult (n=30), diabetes type 1 patients (n=30), hypertensive
patients (n=30), diabetes type 1with hypertension patients (n=29)
into EDTA anticoagulant tubes (randomly selected). Complete blood
counts for all samples were analyzed by using the Sysmex haematological
analyzer, a three-part auto analyzer able to run 19 parameters per
sample including platelet indices (MPV, PDW, and P-LCR). This study revealed significant
difference(p value < 0.05) only in mean age of HT (55.73 ) and platelet count in IDDM
(although its within the lower limit of normal reference range) (172.8 133.6). However, all
other parameters were found to be insignificant (p value > 0.05) for all study population
(IDDM, HT, and IDDM/HT).
Keywords: Platelet indces, Diabetes mellitus, Hypertension.
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