Abstract

PLATELET INDICES AMONG PATIENTS WITH DIABETIC MELLITUS TYPE 1 AND HYPERTENSION IN KHARTOUM STATE

Hussam MA Ibrahim*, Mohanad Altayeb, Ammar B. Omer, Hind Omar, Shima Abu Obaida, Rowaida El-Zubair, Du’aa Abdul Rahman and Umar Babangida

ABSTRACT

Diabetes and hypertension remains as the most imminent disease contributing to the cardiovascular disease burden due to ongoing low grade inflammation. This study was aimed to determine platelet count and platelet indices in diabetic type 1 patient, diabetic type 1 with hypertension and hypertensive patient compared with normal individual to see if there are differences in platelet count and platelet indices among them. In this study venous blood samples were collected from healthy control adult (n=30), diabetes type 1 patients (n=30), hypertensive patients (n=30), diabetes type 1with hypertension patients (n=29) into EDTA anticoagulant tubes (randomly selected). Complete blood counts for all samples were analyzed by using the Sysmex haematological analyzer, a three-part auto analyzer able to run 19 parameters per sample including platelet indices (MPV, PDW, and P-LCR). This study revealed significant difference(p value < 0.05) only in mean age of HT (55.73 ) and platelet count in IDDM (although its within the lower limit of normal reference range) (172.8 133.6). However, all other parameters were found to be insignificant (p value > 0.05) for all study population (IDDM, HT, and IDDM/HT).

Keywords: Platelet indces, Diabetes mellitus, Hypertension.