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Dr. S. Siva Josyaa*, Dr. N. J. Muthukumar and Dr. V. Banumathi


Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. It is a disorder of major public health importance, in terms of its prevalence and suffering, dysfunction, morbidity and economic burden. Depression is more common in women than men. Siddha system of medicine is an ancient system of medicine, which focus on physical, mental, social and spiritual wellbeing of an individual. In Siddha system of medicine, Siddhars who are spiritual scientists have briefly explained about Depression and specific medicines to cure the disease. Thiutharatchatha chooranam is a poly herbal preparation with 14 herbal ingredients which treats psychiatric diseases particularly unmatham (Depression). This review is aimed to bring out the scientific evidence for the therapeutic usage and pharmacological activities of Thirutharatchatha chooranam and focus its its curative nature of the drug. Most of the siddha drugs have antidepressant, antioxidant, anti-inflammatory, sedative and aphrodisiac activity hence justifying its usage in above mentioned disease.

Keywords: Siddha medicine, Thirutharatchatha chooranam, unmatham, pharmacological activity.

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