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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.084

ICV : 90.8

WJPR Citation

	All	Since 2011
Citation	2903	2393
h-index	27	24
i10-index	68	60

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Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

COMPARSION STUDIES ON TRANSDERMAL FILMS OF NATURAL TAMARIND SEED POLYSACCHARIDE EXTRACT CONTAINING ANTI HYPERTENSION DRUG WITH PVA ,HPMC AND GUAR GUM.

M.SantoshNaidu, G.V.Radha, P.Girish1and D.Lohithasu*

ABSTRACT

Objective of the study: The present study was to compare the transdermal film property of the natural Tamarind seed polysaccharide extract with the synthetic and natural polymers like PVA, HPMC and Guar gum. The transdermal films prepared by solvent casting method using Tamarind seed polysaccharide (TSP) alone and combinations with other polymers and film properties are evaluated. The release property of various film forming agent in increasing order are TSP>PVA>guar gum>HPMC. Conclusion: Tamarind seed polysaccharide (TSP) combination has showed the drug retardant property. The order of drug release for different formulation is given as follows F2>F1>F8>F7>F14>F11>F6>F5>F4>F3>F13>F12>F9>F10. Formulated Transdermal Films evaluated for various physicochemical parameters and in vitro permeation studies. Transdermal drug delivery system (TDDS) facilitates delivery of therapeutically effective amount of drug across a patient’s skin with controlled rate.

Keywords: Tamarind seed polysaccharide (TSP), Retardant property, PVA, HPMC and Guar gum.

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