WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

UPDATE OF THE NEUROPROTECTIVE EFFECT OF MAO-B INHIBITORS THERAPY ON PARKINSON’S DISEASE

Rizta Widya Pangestika* and Suharjono

ABSTRACT

Parkinson’s disease was marked by stiffness, bradykinesia, resting tremor, and postural instability occurring due to various causes that were mainly idiopathic causes. Monoamine oxidase B inhibitor, also known as MAO-B inhibitor was crucial for therapy against Parkinson’s disease. The inhibitor metabolized dopamine selectively, blocking one of the enzymes that broke dopamine in brains and enhancing the effects. In Parkinson’s disease, Selegiline was the first generation of MAO-B inhibitors used for therapies; whereas Rasagiline was the second generation of the same inhibitor. The review emphasized the pharmacological aspect, side effect, and neuroprotective effect of Selegiline and Rasagiline on Parkinson’s disease.

Keywords: Parkinson’s disease, neuroprotective effect, MAO-B inhibitors, Selegiline, Rasagiline.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More