WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

INTRINSIC ACTIVITY AND POTENCY DETERMINATION FOR ANTIEMETIC EFFECT OF CHIKADOMA (LUPINUS ARBOREUS)

*Ohadoma S. C. and Chukwu L. C.

ABSTRACT

Objective: To determine the intrinsic activity and potency rating of Chikadoma amongst two other natural remedies for antiemetic activity. Materials and Methods: Copper sulphate emesis technique was employed in the determination of antiemetic activity. The two other plant materials were Elaeis guinensis and Ocimum gratissimum. Five groups (I-V) comprising five (2 weeks old) chicks were used. Group 1 received 0.5 ml distilled water orally and served as negative control. Group II received 50 mg/kg of chlorpromazine orally and served as positive control. Group III, IV and V received 200 mg/kg each of Chikadoma, Elaeis guinensis and Ocimum gratissimum extracts orally respectively. Results: The leaf extract of Chikadoma showed significant intrinsic activity with a potency equal to that of Ocimum gratissimum but less potent than Elaeis guinensis and the positive control, chlorpromazine. Conclusion: The extract of Chikadoma exerted intrinsic activity and high potency for antiemetic effect in chicks.

Keywords: Chikadoma, Lupinus arboreus, Intrinsic activity, Potency, Ocimum gratissimum, Elaeis guinensis, antiemetic effect.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More