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Abstract

A PROSPECTIVE STUDY ON THE ASSESSMENT OF PRESCRIPTION PATTERN AND PROVIDING CLINICAL PHARMACY SERVICES IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND ITS COMORBID DISEASES IN A TERTIARY CARE HOSPITAL

Sreeja M.*, Pavan G., Rakhi S. K. and Anil Babu

ABSTRACT

Diabetes mellitus (DM) is a chronic illness along with disturbance of carbohydrate, protein, and fat metabolism due to defects in insulin secretion and/or insulin response that requires life-long medical care and ongoing patient self-management and support to prevent acute complications and to reduce the risk of morbidity and mortality. Type 2 DM is a metabolic disorder which is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency and it also known as non-insulin dependent diabetes mellitus (NIDDM). Diabetes is often initially managed by increasing exercise and modifying diet. The number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014. The prevalence of diabetes has been seen increased in low income countries. An estimated 3.4 million deaths were reported in 2015 due to diabetes. Almost half the deaths were seen in patients before 70 years. In an article, WHO mentioned that diabetes will be the 7th leading cause of death in 2030. Healthy diet, regular physical activity, etc are some of the ways to prevent the onset of type-2 DM. Diabetes and its complications can be prevented with diet, regular physical activity, medication, regular screening of blood glucose levels. The analysis of our study has shown that in patients with type-2 DM with complications, insulin therapy was preferred over OHAs. In majority cases, insulin therapy was used in combination with OHAs for the better control of diabetes in presence of alarming levels of glycemic levels. INSULIN REGULAR was the first choice of insulin therapy and METFORMIN was the most prescribed OHAs. The result of our study suggest the need for comprehensive management of diabetic patients including dietary changes, life style modifications can control high blood sugar levels. Effectiveness of therapy is influenced by selection of medication, as well as patient adherence with prescribed drug dosage regimens.

Keywords: DM, NIDDM, METFORMIN.


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