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Abstract

“EVALUATION OF PHARMACOPOEIAL STANDARDS WITH HPTLC PROFILE OF AN IMPORTANT UNANI FORMULATION - QURS-E-GULNAR”

Asma Sattar Khan*, Farah Ahmed, Shoeb Ahmed Ansari, Kiran Negi
Anas Iqbal Alvi and Asma Mirza

ABSTRACT

The preparation of classical Unani formulations is based on traditional methods in accordance with the procedures described in classical texts. Lack of modern pharmacopoeial standards for preparation of these formulations results in batch to batch variations and low quality finished products. The increase in the demand for herbal drugs has led to the need for quality standardization of these drugs. The Drug Standardisation Research Unit under the Central Council of Research in Unani medicine, New Delhi is engaged in developing the standards of classical Unani formulations. The Unani polyherbal formulation, Qurs-e-Gulnar known to be effective in the treatment of chronic diarrhoea, has been standardized at the Unit by following modern scientific quality control procedures. The formulation was subjected to various quality control parameters such as organoleptic evaluations (color, odor, taste, and consistency), physicochemical evaluations (loss on drying, total ash, acid insoluble ash, pH of 1 and 10% solution, water soluble matter and alcoholsoluble matter) and HPTLC analysis. The evaluation of contaminants such as heavy metals, aflatoxins, pesticide residues, and microbial contamination was also carried out in the formulation.

Keywords: SOP, Microscopy, pharmacopoeial parameters, HPTLC, Qurs-e-Gulnar, Quality control.


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