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Bincy Babu* and Jisha Helen George


Background: Thiamethoxam is a neonicotinoid insecticide active against a broad range of commercially important sucking and chewing pests. These insecticides act as agonists at. Nicotinic, acetylcholine, receptors, which cause insect paralysis and death. The high specificity for receptors in insects was considered to possess highly selective toxicity to insects and relative sparing of mammals. However, an increasing number of cases of acute neonicotinoid poisoning have been reported in recent years. Case presentation: This is a case report of a man who developed gastrointestinal symptoms and renal failure after ingestion of neonicotinoid insecticide. A detailed literature review found that respiratory, cardiovascular and certain neurological, gastrointestinal, renal presentations are warning signs of severe neonicotinoid intoxication. Conclusion: The amounts of ingested neonicotinoid insecticide and the plasma neonicotinoid concentration are not useful guides for the management of intoxicated patients. Supportive treatment and decontamination are the practical methods for the management of all neonicotinoid-poisoned patients.

Keywords: Neonicotinoid, gastrointestinal, renal failure.

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