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Abstract

EVALUATION OF IN-VITRO MEMBRANE STABILIZATION AND THROMBOLYTIC ACTIVITIES OF RAVENALA MADAGASCARIENSIS SONN

Md. Abul Hassan*, Nafisa Yesmin, Zakia Sultana Sathi and Imtiaj Hossain Chowdhury

ABSTRACT

The aim of the present study was to evaluate the in-vitro membrane stabilization and thrombolytic activities of the methanolic extracts of root and leaves of Ravenala madagascariensis Sonn. Assessment of invitro membrane stabilization activity was carried out by hypotonic solution induced hemolysis method in which both root and leaves extracts along with the standard drug acetyl salicylic acid, significantly (p<0.0001) inhibited hemolysis when compared to control. For illustration, root and leaves extracts caused maximum inhibition of hemolysis of 39.21% and 30.75% respectively. In in-vitro thrombolytic activity test, 39.29% and 22.96% clots were lysed by root and leaves extract respectively which were also of statistical significance (p<0.0001).

Keywords: Ravenala madagascariensis, membrane stabilization activity, thrombolytic activity.


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