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Dr. Krishna Kumar*, D. B. Vaghela**, Harisha C. R.*** and Shukla V. J.****


Oral submucous fibrosis (OSMF) is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the lamina propria and submucosa, that results in marked rigidity and eventually inability to open the mouth. It manifests as blanching and stiffness of the oral mucosa, trismus, burning sensation in the mouth, intolerance to eating hot and spicy foods, repeated vesicular eruption and ulceration of the buccal mucosa, palate and pillars, loss of gustatory sensation, etc. In the management of OSMF Rasayana Yoga as internal medicine was, used Rasayana Yoga Contains is Vata-Kapha Shamaka properties. Most of the drugs are having immunomodulatory, antioxidant, anti-inflammatory, and cancer preventive properties that may have improved the status of Dhatus (tissues). By virtue of Yogavahi (has special affinity to carry and potentiate the action of main drug), Sukshma and Sanskaranuvarti (affinity to carry the properties of main drug along with own) properties, Madhu and Ghrita serve as a best vehicle for the drugs. The present work was carried out to standardize the finished product Rasayana Yoga in terms of its identity, quality and purity. Pharmacognostical and Physicochemical observations revealed the specific characters of all active constituents used in the preparation. The Pharmaceutical analysis showed that the Water soluble extract is 15.8 w/w, Methanol soluble extract is 10.48% w/w Ash value is 8.50% w/w, Loss on drying at 110 C is 6.5% w/w and pH value is 55. HPTLC study of Rasayana Yoga revealed 8 spots at 254 nm and 6 spots on 366 nm.

Keywords: Rasayana Yoga, pharmacognosy, pharmaceutical analysis Sukshma, Sanskaranuvarti.

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