AN EXPERIMENTAL STUDY TO EVALUATE THE EFFICACY OF GUDUCHYADI NIRUHA BASTI IN THE MANAGEMENT OF PARKINSONISM
Dr. Rohit Shrikant Kashikar*, Dr. Niranjan Rao and Sudhakar Bhat
ABSTRACT
Parkinsonism is typically considered a chronic progressive neurodegenerative
movement disorder. In the recent times it was seen that
Constipation is an early indicator and a common symptom which
might be a possible cause for Parkinsonism. This disease is explained
as syndrome comprising of various groups of disorders that can be
attributed to Parkinsonism. One of the very important concepts quoted
in Ayurveda is the Concept of avarana, where the gati, the unique
feature of Vata is obstructed by Kapha dosha, thus leading to the
disease. The best modality for such a disease condition explained by
our Acharyas is the Basti chikitsa. Very few experimental studies have
been taken up, on Basti karma to provide the data proving the efficacy
of this clinically effective procedure. Hence to give preclinical support to the effectiveness of
Guduchyadi niruha basti explained in the classics, this experimental study was selected. For
this a battery of well-known Neuro-muscular tests were selected with main focus on the
efficacy in test protocols supposed to be predictive for the efficacy in treatment of
Parkinsonism namely, Rota rod apparatus, Oxotremorine Test, Anti-Reserpine Test, L-Dopa
Potentiation Test. Significant reversal of symptoms was seen in this work. Therefore from the
data harvested from animal experimentation, it can be concluded that there is definite activity
of Guduchyadi Niruha Basti in the effective management of Parkinsonism.
Keywords: Parkinsonism, Guduchyadi Niruha Basti, Wister Albino Rats, Anti-parkinsonian activity.
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