WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

COMPARATIVE EFFICACY, SAFETY AND COMPLIANCE OF LONG-TERM ANTIBIOTIC TREATMENT WITH SHORT-TERM ANTIBIOTIC TREATMENT IN CHILDREN WITH ACUTE LOWER RESPIRATORY TRACT INFECTION

Isharath Ebrahim*, Divya Sebastian, Nikitha Abraham, Niyas Ahammed A., Jereena E. and Jyothi Vijayan

ABSTRACT

To compare the efficacy, safety and compliance of short-term course of Azithromycin with a long-term course of Amoxicillin-clavulanate in the treatment of children with Acute Lower Respiratory Tract Infection (ALRTI). A prospective observational study was conducted in 172 outpatients diagnosed with ALRTI. Azithromycin was administered as a single dose for 3 days and Amoxicillin-clavulanate was given TID for 7-10 days. The diagnosis of LRTI was based on the presence of clinical signs and symptoms associated with LRTI along with Microbiological evidence chest consolidation. The percentage of patients clinically cured plus improved was 95.3% for Amoxicillinclavulanate whereas 93% for Azithromycin. This difference was not statistically significant (p<0.001) rejecting the null hypothesis that long-term therapy has accelerated efficacy over short-term therapy. More adverse events were found in Amoxicillin-clavulanate group compared to other. An additional advantage of Azithromycin is attributed to the high- compliance due to short therapy and convenience. We concluded that 3-day Azithromycin is as effective as 10-day course of Amoxicillin-clavulanate. Azithromycin has fewer side effects.

Keywords: Amoxiciilin-clavulanate, Azithromycin, compliance, LRTI and PAMAQ.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More