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Abstract

AN OBSERVATIONAL STUDY ON SAFETY PROFILE OF FERRIC CARBOXYMALTOSE INTRAVENOUS INFUSION IN IRON DEFICIENCY ANAEMIA PATIENTS IN A TERTIARY CARE HOSPITAL, BANGALORE

Dr. Brunda M. S.*, Dr. Praveen Kumar, Dr. Prasanth Vas Sahu, Dr. Padmapriya, Dr. Ritty Sara Pharm D.

ABSTRACT

Background: Iron deficiency anaemia accounts for the majority of anaemia. Although iron replacement therapy is effective conventional iron formulations has some disadvantages like Gastro-intestinal side effects for oral formulations and issues like frequent administration for intravenous formulations. Ferric carboxymaltose, which overcomes these limitations and it can be used widely as an intravenous iron sucrose. Ferric carboxymaltose combines with the positive characteristics of iron dextran and iron sucrose but not associated with dextran induced adverse reactions and can be given in higher doses than iron gluconate/sucrose. Objective: The objective of the study is to “Study the safety profile of “FERRIC CARBOXY MALTOSE INTRAVENOUS infusion” in iron deficiency anaemia patients. Materials and Methods: A prospective observational study was carried out in the general medicine department in a Tertiary care hospital, Bengaluru, Karnataka. Data obtained through patient case sheets, medication charts and laboratory data reports. Results: In our present study, the total number of subjects enrolled were 100 and out of 100 patients, 49 were males and 51 were females which resembles the 49% of male patients and 51% of female patients out of counter sample (100%). During the course of study, it has been observed that patients aged 40-80 years with iron deficiency anaemia (60% counter sample) were more in number compared to other group patients. Conclusion: To conclude, although this study had a small size it give us an overall idea about observational study on safety profile of ferric carboxymaltose intravenous infusion in Iron deficiency anaemia patients.

Keywords: Iron deficiency anaemia, Ferric carboxy maltose, Intravenous Infusion, safety profile.


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