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Abstract

STANDARDIZATION OF RASAMRUTAM AND ITS ROLE IN PEPTIC ULCER

Dr. Sheela Pargunde*, Dr. Vaishali Khobragade and Dr. Viveka Kamble

ABSTRACT

Rasagranthas mentioned materials of mineral, herbal and animal origin for preparing herbomineral drug i.e Khalviya rasayan, Parpati rasayan, Pottali rasayan and Kuppipakwa rasayan from shodhit, jarit, marit and satwapatan and other procedures and also mentioned medicinal properties and contraindication of above dravyas and kalpa. Importance of mercury i.e ‘Rasa’ described in all rasagranthas superior to other Maharasa, Uparasa, Sadharan rasa, Vish dravya and Ratna & upratna. Khalviya rasayan is basic and simple preparation method of kalpa among the all preparations. There are some characteristic of this kalpa like, this kapla has more potency, high shelf life, minimum dose and good palatability. Mardan samskara has great importance in kajjalikalpa. In mardan samskara three procedures are taking place, pressure (drug particle size become very fine), friction (regenerate heat), motion (helps in mixing of dravyas and make homogeneous mixture and increase shelf life of kalpa.) Ulcer is defined as a break in the mucosa of the alimentary tract that extends through the muscularis mucosa into the submucosa or deeper. Peptic ulcer is chronic, most often solitary lesion that occurs in any of the gastrointestinal tract exposed to the aggressive action of acid/pepsin juices. Smoking, frequent use of NSAID and steroids, infection of H.pylori are some of the causes of peptic ulcer, which cause acute abdominal pain, haematemesis, bloating, nausea, vomiting, burping etc. leads to discomfort hence there is need to serve a authenticated, standardized, safe and cost effective formulation to the mankind. Rasamrutam a herbomineral formulation mentioned in yaogaratnakar has minimum contents, easy to prepare and will be cost effective & work on this formulation on has not be done, so it is opportunity to work on this kalpa and may serve as one of the effective, substitute drug which will be authenticated and standardized formulation for most acute condition like peptic ulcer in human being.

Keywords: Rasamrutam – Preparation – Standardization – Peptic ulcer.


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