WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS OF 2-(3,4-DICHLORO-BENZOYL)-BENZOIC ACID HYDRAZIDE DERIVATIVES AND ASSESSMENT OF ANTIMICROBIAL EFFICACY AGAINST E. COLI AND B. SUBTILIS

Pallavi Singh*, Anil Kumar Meena, R. K. Singh and Jyoti Singh

ABSTRACT

Emergence of multiple drug resistant microbial species is an arena of serious concern all over the globe. Hydrazone derivatives have been assessed to possess significant antimicrobial, antimycotic, antiinflammatory and anticancerous properties and they have been demonstrated to be a key solution to treat these microbial species which display multiple drug resistance. In current work, a series of hydrazone derivatives were synthesized and evaluated for antibacterial activity against Escherichia coli and Bacillus subtilis using Disc diffusion assay. 2-(3,4-dichloro-bezoyl)-benzoic acid (2-oxo-1,2- diphynyl-ethylidene)-hydrazide (HDZ-1), 2- (3,4-dichloro-bezoyl)-benzoic acid (2-hydoxy- 1,2-diphynyl-ethylidene)-hydrazide(HDZ-2), 2- (3,4-dichloro-bezoyl)-benzoic acid [1-(4- methoxy-phenyle)-ethyledene]-hydrazide (HDZ-3), 2-(3,4-dichloro-bezoyl)-benzoic acid [1- (4-bromo-phenyle)-ethyledene]-hydrazide(HDZ-4) 2- (3,4-dichloro-bezoyl)-benzoic acid [1- (4-chloro-phenyle)-ethyledene]-hydrazide (HDZ-5) were the five key derivatives of hydrazone which were fabricated and tested for antibacterial activity against E.coli and B.subtilis.

Keywords: Hydrazone, E.coli, B.subtilis, Disc diffusion, NMR Spectra.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More