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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.084

ICV : 90.8

WJPR Citation

	All	Since 2011
Citation	2903	2393
h-index	27	24
i10-index	68	60

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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

A REVIEW ON ANALYATICAL METHODS FOR ESTIMATION OF DAPAGLIFLOZIN AND SAXAGLIPTIN IN BULK AND IN PHARMACEUTICAL DOSAGE FORM BY HPLC METHODS

*Yogesh B. Mali, Mairal Pooja B. and Dr. Ambadas R. Rote

ABSTRACT

Dapagliflozin and Saxagliptin are very effectively used treatment for type II diabetes. They are very potent inhibitor of renal glucose reabsorption and dipeptidyl peptidase protein 4 and sodium glucose transport protein 2 and also they are called as DPP4 & SGLT2 inhibitors. They are generally administered as tablets. Determination of Dapagliflozin and Saxagliptin in pharmaceutical dosage form and bulk form, several analyatical methods including UV, HPLC, LC-MS, HPTLC techniques has been developed. Method indicaticating human plasma stability and impurity profiling are also describe for both drugs. For qualitative and quantitative estimation of Dapagliflozin and Saxagliptin these analytical method can be used and it can also be used for its related degradants in bulk formulations and biological fluids.

Keywords: Dapagliflozin, Saxagliptin, RP-HPLC.

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